Sugar coating on immune cells drives psoriasis inflammation

For generations, scientists believed that blood vessel walls held the key to understanding how immune cells invade inflamed skin in psoriasis — that the body's own architecture opened the gate. A team from Lancaster University and the University of Manchester has quietly overturned that assumption, revealing instead that immune cells carry their own sugar-coated armor, called the glycocalyx, and that they actively shed it to slip out of the bloodstream and into damaged tissue. This discovery repositions the immune cell from passive passenger to active agent in its own migration, and in doing s