For generations, the mystery of early pregnancy loss has been written almost entirely in the language of the mother's body — yet more than half of all human conceptions never reach birth, and the father's contribution to that silence has gone largely unexamined. Lacey Luense and her colleagues at Texas A&M are now turning that gaze toward the sperm itself, asking whether epigenetic markings carried by the father — not mutations, but instructions about which genes speak and which stay quiet — might quietly shape, or unshape, the earliest moments of a new life. Funded by a $1.65 million NIH gran
Paternal sperm epigenetics emerge as key factor in early pregnancy loss
Early pregnancy loss affects millions of people globally, with over 50% of human conceptions estimated not to result in live births.