In the long human effort to understand why the body turns against itself, a team of South Korean researchers has taken a significant step forward — merging the vast scale of genomic population data with the intimate resolution of single-cell biology to trace psoriasis from inherited risk to cellular malfunction. Published in Nature Communications, the work led by Hong-Hee Won at Sungkyunkwan University identifies 125 genetic sites linked to psoriasis onset, 17 of them previously unknown, and points toward 50 potential targets for treatment. For the roughly 2% of humanity living with this autoi