In the long search for the roots of Alzheimer's disease, scientists at Houston Methodist have traced a quiet biological corridor between the body's excess fat and the brain's unraveling — a pathway carried by molecules that were always present, but whose dangers only emerge when metabolic balance is lost. The discovery that restoring this balance improved cognitive function in experimental models suggests that what has long seemed like an inevitable decline may, in fact, be a process with a point of intervention. As Alzheimer's cases approach a projected 14 million Americans by 2060, this find