Two psychologists who built a therapy model outperforming global standards by twenty percentage points faced the quiet dilemma that confronts every serious researcher: whether knowledge confined to journals is knowledge truly given to the world. Ciara McEnteggart and Yvonne Barnes-Holmes left tenured security in Ghent to found the PBBT Institute in Dundalk, survived a pandemic that forced their work online, and found their way toward financial sustainability not through investors but through the oldest business logic of all — offering something people need, directly. Their story sits at the in
Mentor's frank advice pivots therapy startup toward profitability
Even if you make a wrong move, it's not a disaster. You just try something else.
What made you actually leave academia? That's not a small decision for someone at your level.
We had something we knew worked—70 percent recovery rates when the standard is 50. But staying in academia meant we'd always be chasing grants, moving wherever the money was, publishing in the right journals to boost university rankings. We felt like we were being controlled by the system.
So you came home and started a business you'd never done before. Then the pandemic hit immediately.
Yes. We'd imagined ourselves on planes, teaching workshops everywhere. Instead, we learned Zoom overnight and went digital. It felt like a disaster at the time, but it actually made us global. Therapists with full-time jobs could train when it suited them.
But you were still struggling to find a path to profitability.
We were spending all our time chasing investment. A year of that, and we weren't actually building the business. Then Frank Madden kept saying the same thing in Cork: don't forget about services. We could deliver therapy ourselves.
That seems obvious in hindsight.
It does now. But we were academics. We thought of ourselves as trainers, not clinicians running a clinic. We had to give ourselves permission to be both.
And now you're close to profitable.
The clinic launches in September. But it's bigger than that. Therapists trained in our model tell us they can finally take on complex cases they used to refuse. That's the real measure.
The Pulse
- A therapy model achieving 70% recovery rates — against a 50% global benchmark — was at risk of remaining locked inside academic literature unless its creators were willing to abandon the careers that produced it.
- The pandemic dismantled their original vision of in-person global workshops almost the moment they founded the company, forcing a digital pivot that ultimately widened their reach beyond what planes and conference rooms could have managed.
- A year of chasing investors and fundraising pulled McEnteggart away from the work itself, exposing the fragility of a growth model built on external capital rather than earned revenue.
- A single weekend of mentorship at Ballymaloe reoriented the entire business: a mentor's repeated insistence on the value of services prompted the founders to dismantle their model and launch direct therapy delivery within weeks.
- A clinic opening in September is expected to carry the PBBT Institute into profitability — and to address therapist burnout at the same time, as clinicians trained in the method report newfound capacity to take on the most complex cases they once refused.
Two psychologists who built a therapy model outperforming global standards by twenty percentage points faced the quiet dilemma that confronts every serious researcher: whether knowledge confined to journals is knowledge truly given to the world. Ciara McEnteggart and Yvonne Barnes-Holmes left tenured security in Ghent to found the PBBT Institute in Dundalk, survived a pandemic that forced their work online, and found their way toward financial sustainability not through investors but through the oldest business logic of all — offering something people need, directly. Their story sits at the intersection of scientific conscience and commercial reality, a reminder that bringing a genuine breakthrough to scale requires a different kind of courage than the one that produced it.
Ciara McEnteggart and Yvonne Barnes-Holmes built something quietly extraordinary inside Ghent University — a process-based behavior therapy model delivering recovery rates of 70 percent or higher, against a global industry standard of 50 percent. After five years abroad, they faced the question that haunts every researcher with a genuine discovery: publish and move on, or risk everything to put it to work in the world.
They chose the risk. Both held PhDs from Maynooth University, where they had first met as student and professor. Barnes-Holmes had become Ireland's most cited female psychologist. But neither wanted their life's work to live only in academic citations. In 2020, they returned to Ireland and founded the PBBT Institute in Dundalk — and walked almost immediately into a pandemic that made their original plan, built around in-person workshops worldwide, impossible. The forced move to digital delivery turned out to be a quiet gift, making their training accessible to working therapists across the globe.
The business, however, was struggling to sustain itself. McEnteggart spent a year chasing investment, pulled away from the work she had left academia to do. Growth was real but slow, and the path to profitability remained unclear.
Last October, she attended the Entrepreneur Experience at Ballymaloe House Hotel in Cork — a weekend pairing 24 emerging founders with seasoned business leaders. One mentor, Frank Madden, kept returning to the same point across their sessions: don't overlook services. If you can deliver them, do it. McEnteggart returned to Dublin on Monday, blocked out the day with Barnes-Holmes, and they began rebuilding their model from the ground up. They had been so focused on training other therapists that they had never fully considered offering therapy directly. Within weeks, two new revenue-generating products were live.
A clinic opening in September — delivering PBBT online through therapists they have personally trained — is expected to push the business into profitability. The shift matters beyond the balance sheet. Ninety percent of therapists report work-related stress, and burnout runs through the entire field. But therapists trained in PBBT describe something different: a new capacity to take on the most complex clients they once turned away. The method, it turns out, sustains the people delivering it as much as those receiving it.
The PBBT Institute remains entirely founder-owned. What began as a leap from academic security has become something harder to categorize — therapy company, training institute, clinic — and a business that is finally learning to grow on its own terms.
Ciara McEnteggart and Yvonne Barnes-Holmes had built something remarkable in the quiet labs of Ghent University. Their process-based behavior therapy model was delivering recovery rates of 70 percent and higher—compared to the 50 percent industry standard across all therapies worldwide. After five years abroad with their research team, they faced a choice that most academics never have to make: stay in the safe world of published papers and university rankings, or risk everything to put their discovery into the hands of working therapists.
They chose the latter. Both women held PhDs from Maynooth University, where they had first met as student and professor. Barnes-Holmes had become Ireland's most highly cited female psychologist, with more than 160 scientific articles to her name. But neither wanted their life's work confined to the rarefied world of academic citations. "We felt what we were doing deserved to have a place in the world," McEnteggart says, "but if we'd stayed it would have meant continuing to chase grants and move to wherever the money led us." In 2020, they returned to Ireland and founded the PBBT Institute in Dundalk, leaving secure academic positions behind.
The timing was catastrophic. Lockdown arrived almost immediately. They had imagined themselves on planes, teaching workshops in rooms around the world. Instead, they were forced to learn Zoom and move their entire operation online—a pivot that, in hindsight, saved them. The digital model made their training accessible to therapists with full-time jobs across the globe. But the business itself was struggling. McEnteggart spent a year chasing investment and fundraising, pulling her away from the work itself. The company was growing, but slowly, and the path to sustainability remained unclear.
Last October, McEnteggart attended the Entrepreneur Experience at Ballymaloe House Hotel in Cork, where 24 emerging founders are paired with seasoned business leaders for a weekend of intensive mentoring. She worked with Julian Costley, an investor in technology and media, who pushed her to think deeper about every aspect of the business. But it was Frank Madden, founder of the Cork-based automation company that would become Catalyx, who shifted something fundamental in her thinking. In the small group sessions, Madden kept returning to the same point: don't overlook services. If you have the capacity to deliver them, do it.
The message landed. McEnteggart returned to Dublin on Monday morning, blocked out the entire day with Barnes-Holmes, and they began dismantling their business model. They had been so focused on training other therapists that they hadn't fully considered offering therapy directly themselves. Within weeks, they launched two new revenue-generating products. By September, they planned to open a PBBT clinic delivering therapy online through therapists they had directly trained. The shift was profound: instead of chasing investment to fund growth, they would grow through revenue.
The clinic launch is expected to push the business into profitability. More importantly, it addresses a crisis that runs through the entire mental health field. Ninety percent of therapists report some level of work-related stress. Burnout is endemic. But therapists trained in PBBT report something different. They tell McEnteggart: "I used to turn down complex clients all the time. I would never see someone with a particular type of suffering, but now I feel like I can take on any client." The therapy works not just for patients but for the people delivering it.
McEnteggart's confidence as a businesswoman has grown alongside the company. She arrived at Ballymaloe hesitant, still thinking like an academic. "I was a confident academic, but I wasn't a confident businesswoman," she says. "At the start, we did things very conservatively." Now, she understands that a wrong move isn't a disaster—it's just a signal to try something else. The PBBT Institute still owns 100 percent of itself, with no external investors. What began as a leap of faith from the security of academia has become something harder to categorize: a therapy company, a training institute, a clinic, a business that is finally learning to sustain itself.
Notable Quotes
We felt what we were doing deserved to have a place in the world, but if we'd stayed it would have meant continuing to chase grants and move to wherever the money led us.— Ciara McEnteggart
I used to turn down complex clients all the time. I would never see someone with a particular type of suffering, but now I feel like I can take on any client.— Therapists trained in PBBT, paraphrased by McEnteggart