As populations age and the boundaries of medicine expand, researchers are beginning to name what clinical intuition has long sensed: that frailty and cardiovascular disease are not merely companions in older bodies, but participants in a shared biological story. A new narrative review proposes cardiovascular frailty as a distinct phenotype—a convergence of vascular stiffening, blood pressure dysregulation, and chronic inflammation that accelerates vulnerability in aging adults worldwide. The proposal is not yet a clinical tool, but it is an invitation to look more carefully at the mechanisms t
Cardiovascular frailty emerges as distinct phenotype linking heart health and aging
Frailty increases vulnerability to health decline in older adults, affecting their independence and quality of life.