Autophagy modulation offers new hope against cisplatin-resistant gastric cancer

Gastric cancer remains one of the world's most lethal malignancies, and the chemotherapy drug most commonly deployed against it—cisplatin—frequently loses its power as tumors learn to survive it. A new review of the scientific literature turns attention toward autophagy, the cell's own recycling system, as a lever that might restore chemotherapy's effectiveness. The insight is subtle: autophagy is neither purely enemy nor ally, but a process that, if steered rather than simply suppressed, could tip the balance back toward the patient. Existing medicines and natural compounds already known to m