Ancient DNA shows Gravettian peoples across Ice Age Europe were linked by long-distance gene flow

Eastern and western Europeans were not as isolated as assumed
Pere Gelabert's team found a 30,000-year-old woman from Isturitz carried both western and eastern ancestry.
Mark

Why does one woman from Isturitz matter so much?

Mimi

Because her genome carries both signals. Mostly western ancestry, but also a share related to central and eastern Europe, dated to roughly 32,500 to 31,500 years ago.

Mark

So east and west weren't separate worlds.

Mimi

That's the claim. Earlier genetic data suggested stable eastern and western groups, while the archaeology suggested wide contact. This reconciles the two.

Luke

Worth noting how much rests on few individuals. The Isturitz woman and a previously studied person from Ormesson show the signal. The source doesn't say how many people it takes to call this typical.

Mimi

Fair. The Isturitz-as-meeting-place idea is also framed as something the evidence supports, not something proven.

Mark

And the El Mirón sediment?

Mimi

Human nuclear DNA from a 22,000-year-old layer, with no bones or teeth. It shows western ancestry lasting through the Last Glacial Maximum.

Luke

That backs Iberia as a refuge, but it's one site's layer. It supports the idea; it doesn't settle it.

Mark

What about the Italian fetus?

Mimi

Ostuni1b's parents were from the same population but not closely related, which the team reads as mating practices that limited inbreeding.

Luke

"Suggesting" is the key word there. The mechanism behind it is not established.

  • A single woman's genome from Isturitz has unsettled the long-held picture of two isolated Ice Age populations, revealing gene flow across thousands of kilometers.
  • Her ancestry carries echoes of central and eastern Europe, dated to roughly 32,500 to 31,500 years ago, a meeting that surprised researchers who expected little contact.
  • At El Mirón Cave, scientists drew human genetic information from sediment alone, reading ancestry from a 22,000-year-old layer with no bones or teeth in sight.
  • The Iberian lineage appears to have held its ground through the Last Glacial Maximum, strengthening the case for the peninsula as an Ice Age refuge.
  • The team is now combining sedimentary DNA with proteomics to trace early trans-European expansions and the encounters with carnivores that shaped them.

Some thirty thousand years ago, a woman lived and died in the limestone shelter of Isturitz in southwestern France, and in her ancient bones lies a quiet revision of how the Gravettian peoples of Ice Age Europe knew one another. For decades the genetic record had sketched eastern and western populations as largely separate worlds, linked only by the traded shells, tools, and art that archaeologists found scattered across the continent. Now the traces of the woman's DNA suggest that those distant communities did, at times, mix their lineages, and that this cave may once have been a place where strangers met. Elsewhere, the researchers found that some ancestries endured in place across the bitter millennia of the Last Glacial Maximum, even where no bones remained to tell the tale.

In Isturitz Cave, in southwestern France, the remains of a woman who died about 30,000 years ago have yielded the oldest genome-wide data yet recovered from a modern human in southwestern Europe. Her DNA, reported in Science Advances by a team at the University of Vienna, is reshaping how scientists see the Gravettian world, a culture that spread across much of the continent between roughly 34,000 and 25,000 years ago. Archaeology had long hinted at wide contact between far-flung groups, but genetics had painted eastern and western populations as stable and largely separate.

The woman complicates that portrait. Most of her ancestry traced to the western lineage, yet she also carried ancestry linked to central and eastern European peoples, a mixing dated to around 32,500 to 31,500 years ago. A similar signal appeared in an earlier individual from Ormesson, France. Together with the archaeological evidence, the findings suggest Isturitz may have been a meeting place for different groups. First author Pere Gelabert described the results as proof that eastern and western populations were less isolated than assumed.

Continuity told a parallel story. Genomes from Chufín Cave in northern Spain show western ancestry persisting there for thousands of years. At El Mirón Cave in Cantabria, the team worked from sediment rather than skeletons, recovering human nuclear DNA from a 22,000-year-old layer that held no bones or teeth. The Iberian ancestry found there endured through the Last Glacial Maximum, lending support to the idea of the peninsula as an Ice Age refuge. Senior author Ron Pinhasi said sedimentary DNA can link archaeological layers to the people who once lived on a site when remains are missing.

In southern Italy, the researchers examined Ostuni1b, a male fetus likely the son of a woman studied earlier. The father probably shared the same genetic population, yet the parents were not closely related, suggesting mating practices that kept inbreeding in check. Taken together, the studies show that local continuity and long-distance exchange could coexist. The team now plans to pair sedimentary DNA with advanced proteomics to explore the first trans-European expansions of modern humans and their encounters with carnivores at sites where organic remains are scarce.

A woman who died in Isturitz Cave, in southwestern France, about 30,000 years ago has given researchers the oldest genome-wide data set yet recovered from a modern human in southwestern Europe. Her DNA is at the center of a new study in Science Advances, led by a team at the University of Vienna, that changes how the Gravettian world looks from a genetic point of view.

The Gravettian was one of Europe's major Paleolithic cultures, widespread across the continent from roughly 34,000 to 25,000 years ago. Archaeological finds had long hinted at extensive contacts between far-flung groups. Genetic data, however, had pointed to relatively stable ancestry groups in the east and the west, with little sign of mixing between them.

The woman from Isturitz complicates that picture. Most of her ancestry was related to the western European lineage. But she also carried ancestry related to populations from central and eastern Europe. Genetic modeling places that gene flow at around 32,500 to 31,500 years ago. A similar signal turned up in a previously studied individual from Ormesson, France. Combined with archaeological evidence, the findings support the idea that Isturitz may have served as a meeting place for different groups.

"Our results show that eastern and western European populations were not as genetically isolated as previously assumed," said first author Pere Gelabert, of the Department of Evolutionary Anthropology at the University of Vienna. He added that gene flow across such distances gives a new dimension to how Gravettian populations were connected.

The study also found continuity. Genomic data from Chufín Cave in northern Spain show that western European ancestry persisted in that region over thousands of years. At El Mirón Cave in Cantabria, the team went further, working from sediment rather than skeletons. They recovered enough human nuclear DNA from a 22,000-year-old layer to determine its genetic ancestry, even though no human bones or teeth were present. That ancestry persisted through the Last Glacial Maximum, which supports the view of the Iberian Peninsula as an Ice Age refuge.

Senior author Ron Pinhasi, also of the Department of Evolutionary Anthropology at Vienna, whose team led the work, said sedimentary DNA lets researchers recover genetic information from periods when human remains are missing. In his words, it offers a way to connect archaeological layers with the ancestry of the people who occupied a site.

In southern Italy, the researchers analyzed Ostuni1b, a male fetus most likely the son of Ostuni1, a woman studied earlier. His father probably came from the same genetic population, yet the parents were not closely related. The team reads this as suggesting mating practices that helped avoid high levels of inbreeding.

Taken together, the results show that regional continuity and long-distance exchange could exist side by side. Gelabert's team is now pairing sedimentary DNA with advanced proteomic analyses to investigate the first trans-European expansions of modern humans, and their interactions with carnivores, at sites where organic remains are scarce.

Eastern and western European populations were not as genetically isolated as previously assumed.
— Pere Gelabert, University of Vienna
Sedimentary DNA allows recovery of genetic information from periods where human remains are missing.
— Ron Pinhasi, University of Vienna
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