Study reveals tau's mitochondrial disruption mechanism in Alzheimer's disease

For generations, Alzheimer's disease has resisted our attempts to understand it fully, its cruelties unfolding through mechanisms that remained just beyond reach. Now, researchers have traced a newly discovered path of destruction: the tau protein, long implicated in neurodegeneration, infiltrates the mitochondria of nerve cells and reverses the very flow of electrons that keeps neurons alive. This finding does not merely add a detail to an existing map — it redraws the territory, suggesting that the disease's power to kill neurons may persist even when other aspects of tau's behavior are cont