Study links herbicide picloram to rising early-onset colorectal cancer risk

Early-onset colorectal cancer is more aggressive and metastatic at diagnosis than traditional colorectal cancer, affecting younger populations with potentially greater lifetime impact.

For decades, colorectal cancer was understood as a disease that arrived late in life, a consequence of time's slow accumulation. Now, as younger people under fifty are diagnosed at rising rates with more aggressive forms of the disease, researchers have begun asking what in the modern environment may have changed the terms of that old arrangement. A study published in Nature Medicine points toward picloram, a herbicide in use on American farmland since 1964, using the chemical memory written into patients' own DNA to reconstruct a history of exposure that individual recollection could never pr

Study links herbicide picloram to rising early-onset colorectal cancer risk

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