Study identifies depression, delirium as early PSP warning signs years before diagnosis

Progressive supranuclear palsy causes balance problems, eye movement dysfunction, and cognitive decline, with most patients initially misdiagnosed as having Parkinson's disease, delaying proper treatment by years.

For the many who live years under the wrong diagnosis, progressive supranuclear palsy has long been a disease that announces itself too late. A large British study, drawing on two decades of health data from half a million adults, has now identified five conditions — among them depression and episodes of delirium — that may signal the disease's quiet arrival up to a decade before its most devastating symptoms appear. In the long human struggle to meet illness before it overwhelms, this research offers something rare: a window.

Study identifies depression, delirium as early PSP warning signs years before diagnosis

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