USP Scientists Develop Biodegradable Plant Sensors That Detect Pesticides in Minutes

A sensor that costs less than a dime and dissolves when you're done
The technology makes rapid pesticide testing economically feasible for farms and food safety inspectors.

In a laboratory at the University of São Paulo, researchers have answered a quiet but consequential question: what if the tools we use to protect food did not themselves harm the earth? By fashioning sensors from cellulose acetate — a material born of plants and destined to return to them — a team led by Paulo Augusto Raymundo-Pereira has created a device that detects pesticide contamination on fruit and vegetables in under four minutes, at a cost of less than a dime, closing a gap between agricultural reality and the kind of real-time environmental awareness that modern life demands.

  • Brazil's agricultural economy had no equivalent to the wearable health sensors Raymundo-Pereira studied abroad — a blind spot in a nation where farming shapes the national livelihood.
  • Existing pesticide sensors were made from petroleum-based plastics that couldn't conform to the curved, irregular surfaces of real fruit and left behind persistent waste — the very problem they were meant to address.
  • The new sensor sticks directly to an apple or pepper, accepts a single drop of water, and wirelessly transmits results identifying three pesticide classes to a smartphone in three minutes and twenty-eight seconds.
  • At $0.077 per unit, the technology is designed for the field, not the laboratory — placing rapid contamination screening within reach of farmers and food safety inspectors with minimal equipment.
  • The sensor's biodegradable substrate can be burned to recover its carbon ink for reuse, and early tests on human saliva and tap water suggest the technology may soon extend well beyond agriculture.

At the Instituto de Física de São Carlos, researchers have built a sensor small enough to rest on a leaf — one that detects pesticides on fruit in just over three minutes and costs less than a dime. Made from cellulose acetate printed with carbon ink onto a flexible bioplastic sheet, it conforms to the skin of an apple or pepper, requires only a drop of water, and sends results wirelessly to a smartphone.

The project began with a gap Paulo Augusto Raymundo-Pereira noticed while studying wearable health sensors in California. Brazil, with its vast agricultural economy, had no plant equivalent. The sensors that existed were petroleum-based, rigid, and non-biodegradable — poorly suited to the curved, irregular surfaces of real produce. His team set out to build something that fit the actual conditions of farming.

Each sensor contains two analytical units capable of simultaneously identifying diquat, carbendazim, and difenilamina — three commonly used pesticide compounds. Testing mirrored real-world conditions: fruit was sprayed, left to dry for five hours, then analyzed on-site using a commercial wireless potentiostat and a smartphone. The full process took three minutes and twenty-eight seconds.

The economics matter as much as the chemistry. At $0.077 per unit, the sensors are disposable by design, making them practical for widespread use without specialized infrastructure. When spent, they can be burned under controlled conditions to recover the carbon ink, which feeds back into manufacturing new devices.

The team has already tested the same technology on human saliva and tap water spiked with pesticides, pointing toward future applications in drinking water safety and human exposure screening. Patent applications have been filed, and the research was published in Biosensors and Bioelectronics: X. What the work ultimately proposes is a shift in philosophy: that monitoring for contamination need not be a laboratory procedure, and that the instruments of food safety need not outlast the food itself.

At the Instituto de Física de São Carlos at the University of São Paulo, researchers have built something small enough to fit on the tip of a leaf: a sensor that can tell you whether pesticides are present on an apple or pepper in just over three minutes. The device costs less than a dime. It is made from cellulose acetate—the same material used in old film stock—printed with carbon ink onto a transparent, flexible bioplastic sheet. Stick it to the skin of a fruit, add a single drop of water, and it will detect three different classes of pesticides simultaneously while sending the results wirelessly to your phone.

The work emerged from a straightforward observation. Paulo Augusto Raymundo-Pereira, the lead researcher, had spent time at the University of California studying wearable sensors designed to monitor human health through sweat and saliva. He realized that Brazil, where agriculture drives a substantial portion of the nation's economy, had no equivalent technology for plants. The existing sensors on the market were made from petroleum-derived plastics that struggled to conform to the curved and irregular surfaces of leaves, stems, and fruit. They were also not biodegradable. Raymundo-Pereira and his team set out to build something better.

The sensor itself is deceptively simple in concept. Each device contains two separate sensing units that employ different analytical techniques to identify diquat, carbendazim, and difenilamina—three pesticide compounds commonly used in agriculture. The cellulose acetate substrate is flexible enough to mold itself to whatever surface it touches, whether that is the waxy skin of an apple or the ridged surface of a pepper. The material is atoxic, thermally stable, lightweight, and easy to handle. Most importantly, it is biodegradable. When a sensor has been used, it can be burned under specific conditions to recover the carbon ink, which is then used to manufacture new devices. Nothing is wasted.

The testing process mirrors real-world conditions. Researchers sprayed a pesticide solution onto the skin of apples and peppers at a concentration of 1,000 micrometers, then allowed the fruit to dry for five hours. They then placed the sensor directly on the dried surface, added a 500-microliter drop of phosphate buffer solution—a liquid that stabilizes the electrical environment—and initiated the measurement. The portable wireless potentiostat, a device that controls voltage and measures electrical current to detect and quantify chemical substances, processed the data and transmitted results to a smartphone via Bluetooth. The entire analysis took three minutes and twenty-eight seconds.

The economics of the technology are striking. Each sensor costs $0.077 to produce. Because they are designed for single use—a practical necessity given the nature of pesticide residue testing—they must be inexpensive and disposable. The low cost makes widespread adoption feasible for farmers and food safety inspectors who might otherwise lack access to rapid testing methods. The wireless potentiostat is a commercial off-the-shelf device, meaning the barrier to entry is minimal. A farmer or distributor needs only the sensors themselves and a smartphone.

Raymundo-Pereira's team is not stopping at agriculture. The same sensor technology has already been tested on human saliva and tap water, both spiked with pesticides to simulate real contamination. The results suggest the sensors could be adapted to detect pesticide residues in drinking water supplies or to screen for exposure in human populations. The technology also has potential applications in detecting other compounds—metabolites in urine and sweat, biomarkers of disease, nutrient levels in soil. The researchers have filed patent applications for both the earlier wearable glove prototype and this new plant-mounted sensor. The work was published in February in the journal Biosensors and Bioelectronics: X, and the research was supported by the São Paulo Research Foundation through postdoctoral fellowships and research grants.

What distinguishes this technology from existing wearable sensors is not just the material but the philosophy behind it. Petroleum-based plastics are durable but persistent—they linger in the environment for centuries. Cellulose acetate, derived from agricultural waste, returns to the earth. The sensor can be applied directly to the plant surface, conforming to its shape, rather than requiring manipulation by hand. For a farmer checking fruit before harvest or a food safety inspector at a distribution center, the difference is practical: faster results, lower cost, and the knowledge that the device itself will not become another piece of plastic waste. The technology points toward a future in which monitoring for contamination is not a specialized laboratory procedure but something that can happen in the field, in real time, with minimal friction and minimal environmental cost.

The sensors enable non-destructive, rapid, on-site, and decentralized detection, providing real-time biological information about the plant's health and environmental factors
— Paulo Augusto Raymundo-Pereira, Instituto de Física de São Carlos (IFSC-USP)
Because much of Brazil's GDP is concentrated in agriculture, I thought: why not adapt the technology for plants instead of humans?
— Paulo Augusto Raymundo-Pereira, on the inspiration for the project
A Conversa do Hearth Outra perspectiva sobre a história
Inventor

Why does it matter that these sensors are biodegradable? Couldn't a farmer just throw away a plastic sensor and move on?

Model

The scale changes everything. If you're testing hundreds of fruit samples across a harvest season, you're generating hundreds of sensors. Plastic accumulates. Cellulose acetate breaks down. But there's another layer—the carbon ink can be recovered and reused. So the material itself becomes a resource rather than waste.

Inventor

Three minutes seems fast, but is it fast enough for a real farm operation?

Model

It depends on the workflow. If you're spot-checking fruit at a packing facility, three minutes per sample is manageable. You're not testing every single apple. You're testing enough to verify that your pesticide residue levels are within safe limits. The real advantage is that you can do it on-site, immediately, rather than sending samples to a lab and waiting days for results.

Inventor

The sensor costs less than a dime. How is that economically viable for the researchers?

Model

The value isn't in selling individual sensors at high margins. It's in the intellectual property—the method, the material composition, the integration with wireless readout. The patent applications are already filed. Once the technology is licensed or adopted at scale, the unit cost becomes almost irrelevant. The real money is in the platform.

Inventor

You mentioned the sensor was tested on human saliva and tap water. Does that mean it could become a consumer product?

Model

Potentially, yes. Imagine a home water testing kit or a way to screen for pesticide exposure in your own body. But that's further down the road. Right now, the focus is agricultural—that's where the immediate need is, and where the technology was designed to work.

Inventor

What happens to the sensor after it's been used? Does it just dissolve?

Model

Not immediately. It's biodegradable, meaning it will break down over time in the right conditions. But the researchers also figured out how to burn it under specific conditions to recover the carbon ink. So you don't have to wait for nature to do the work. You can actively recycle it into new sensors.

Inventor

Why hasn't this been done before?

Model

Partly because the focus in wearable sensors has been on human health applications—monitoring athletes, patients, people in hospitals. The agricultural adaptation was a deliberate choice by Raymundo-Pereira after his time in California. He saw the technology and thought: Brazil's economy runs on agriculture. Why not build this for plants instead of people?

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