Scientists identify overlooked malaria vaccine targets to boost protection

Malaria kills over 500,000 people annually, predominantly young children in Africa, making vaccine improvements critical for reducing childhood mortality.

For generations, malaria has claimed the lives of children before they could learn to speak their own names, and the vaccines designed to stop it have offered only partial shelter. Scientists at the Ragon Institute have now identified a structural blind spot in the two WHO-approved vaccines — both of which train the immune system on only one region of the parasite's protein coat, leaving stronger antibody targets unrecognized. By adding short peptide fragments to the existing vaccine approach, researchers were able to awaken all three relevant immune responses at once, pointing toward a more c

Scientists identify overlooked malaria vaccine targets to boost protection

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