From the ancient fruit of the pomegranate, science has drawn a compound that may offer new hope to the hundreds of thousands living in quiet suffering with a form of heart failure that medicine has long struggled to address. Researchers at King's College London have found that urolithin A, produced naturally in the body after consuming pomegranates and certain nuts and berries, improved heart function by up to 80% in laboratory models of heart failure with preserved ejection fraction — a condition where the heart pumps adequately but cannot relax and fill with blood as it should. The discovery
Pomegranate compound urolithin A shows 80% improvement in hard-to-treat heart failure
Nearly 500,000 people in the UK with heart failure with preserved ejection fraction experience breathlessness, fatigue, reduced exercise ability and poor quality of life due to limited treatment options.