Iran retaliates with missile strikes after U.S.-Israel kills Khamenei

At least 115 people killed in a girls' school strike in southern Iran; one woman killed in Tel Aviv from Iranian missile; one killed in UAE from shrapnel; dozens wounded across multiple locations.
You have crossed our red line and must pay the price.
Iran's parliamentary speaker vowed devastating retaliation hours before launching hundreds of missiles and drones across the region.

In the long and turbulent history of the modern Middle East, few moments carry the weight of what unfolded on a Saturday morning in Tehran, when a joint American and Israeli strike killed Iran's Supreme Leader Ali Khamenei, ending a decades-long reign and shattering the architecture of power that had defined the Islamic Republic since 1979. Within hours, Iran answered with hundreds of missiles and drones aimed at Israel and American installations across the Gulf, striking civilian and military targets alike and killing scores of people, including children at a girls' school. The world now watches a region teetering between calculated deterrence and the kind of cascading violence that, once begun, has rarely known a clean end.

  • The killing of Khamenei — along with the Revolutionary Guard commander, defense minister, and senior security adviser — left Iran's government suddenly headless, scrambling to form an emergency council while the nation split between grief and quiet celebration.
  • Iran's retaliation was swift and vast: hundreds of missiles and drones rained down on Israel, Bahrain, Kuwait, Qatar, and the UAE, with explosions rocking Dubai's port and shrapnel killing a woman in Tel Aviv.
  • The most devastating blow fell not on a military target but on a girls' school in southern Iran, where at least 115 people were killed — a strike that drew international alarm even as the U.S. military said it was still investigating.
  • Trump met Iranian threats with escalating ultimatums, promising a force 'never seen before' if Iran struck again, while Democrats challenged the legality of an operation conducted without congressional authorization.
  • The Strait of Hormuz — through which a significant share of the world's oil flows — now hangs in the balance, as the question of whether Iran will strike again, and whether the United States will follow through, remains unanswered.

On a Saturday morning during Ramadan, American and Israeli forces carried out a strike on Tehran that killed Iran's Supreme Leader Ali Khamenei, 86, along with the commander of the Revolutionary Guard, the defense minister, and a senior security adviser. The operation, planned over months, came amid deepening tensions over Iran's nuclear program — a program Trump had claimed to have crippled the previous year, only for intelligence to show it quietly rebuilding. Several of Khamenei's relatives, including a daughter and grandchild, were also reported killed.

The news split Tehran. Some residents climbed to rooftops to cheer; others prepared for mourning as the government declared 40 days of national grief. A black flag rose over the Imam Reza shrine in Mashhad. But Iran's formal response came not in sorrow but in force: within 12 hours, parliament speaker Mohammad Bagher Qalibaf appeared on state television to promise devastating blows, and the Revolutionary Guard launched what it called its most intense offensive operation ever.

Hundreds of missiles and drones struck Israeli and American targets across the Gulf — in Bahrain, Kuwait, Qatar, and the UAE. Many were intercepted, but not all. A woman in Tel Aviv was killed by shrapnel. Explosions damaged Dubai's port and scarred the Burj Al Arab. Drones hit Kuwait's international airport. In southern Iran, at least 115 people died when a girls' school was struck — a civilian target whose destruction drew urgent international scrutiny. Flights across the region were grounded, and air defense fire echoed over cities through Sunday morning.

Trump responded with characteristic escalation, warning on social media that any further Iranian strikes would be met with force 'never seen before.' He had already called Khamenei one of history's most evil figures and framed his death as Iran's chance at liberation. Democrats in Congress objected that the operation had proceeded without legal authorization; the White House said key leaders of both parties had been briefed beforehand.

With Iran's leadership decapitated and its retaliation already underway, the region now faces the question that no one has yet answered: whether the cycle of strikes and counter-strikes can be contained before it pulls the wider world into a war that no one — not even those who started it — can fully control.

The Supreme Leader of Iran was dead, killed in a surgical strike by American and Israeli forces on Saturday morning at his office in Tehran. Within hours, the country's leadership confirmed it. Within a day, Iran had fired hundreds of missiles and drones across the region in response, and the Middle East had lurched into a new and more dangerous phase of conflict.

Ayatollah Ali Khamenei, 86 years old, had ruled Iran for decades—the second supreme leader since the 1979 revolution, with final authority over every major decision the government made. His death created an immediate vacuum. The Revolutionary Guard, the clerical establishment, the security apparatus—all answered to him. Now there was no clear successor, and the country scrambled to form a governing council while the body was barely cold.

The operation had been planned for months, officials said. It came during Ramadan, at the start of the Iranian workweek, and followed months of escalating tensions under the Trump administration. The president had already claimed victory over Iran's nuclear program in strikes the previous year, but intelligence showed the country rebuilding—developing the capacity to produce its own centrifuges, the machinery needed to enrich uranium to weapons grade. Trump wanted a deal to constrain the program. Iran said it hoped to avoid war but would not surrender its right to enrich. The gap between those positions had no bridge.

When news of Khamenei's death spread through Tehran, the response split the city. Some residents climbed to rooftops, cheering, blowing whistles, ululating into the night. Others prepared for mourning—the government declared 40 days of public grief and a seven-day national holiday. A black flag rose over the Imam Reza shrine in Mashhad. State media reported that several of Khamenei's relatives had also been killed in the strike, including a daughter, a son-in-law, and a grandchild.

But the immediate Iranian response was not introspection. It was force. Within 12 hours, Iran's parliament speaker, Mohammad Bagher Qalibaf, appeared on state television. "You have crossed our red line," he said. "We will deliver such devastating blows that you yourselves will be driven to beg." The Revolutionary Guard promised its "most intense offensive operation" ever. Hundreds of missiles and drones launched toward Israel and toward American military installations scattered across the Gulf—in Bahrain, Kuwait, Qatar. The Israeli military said many were intercepted. But not all.

A woman in the Tel Aviv area was killed by shrapnel. In Dubai, explosions rocked the port and scarred the facade of the Burj Al Arab. In southern Iran, at least 115 people died when a girls' school was struck—a school, not a military target, though the U.S. military said it was aware of reports and looking into them. Dozens more were wounded across the region. In Kuwait, drones hit the main international airport. In Bahrain, three buildings were damaged in the capital. In Jordan, air defenses dealt with 49 drones and ballistic missiles. Flights across the Middle East were disrupted. Air defense fire thundered over cities into Sunday morning.

Trump responded to Iranian threats the way he had responded to the killing itself—with escalation. "Iran just stated that they are going to hit very hard today, harder than they have ever hit before," he wrote on social media. "THEY BETTER NOT DO THAT, HOWEVER, BECAUSE IF THEY DO, WE WILL HIT THEM WITH A FORCE THAT HAS NEVER BEEN SEEN BEFORE!" He had called Khamenei "one of the most evil people in History" and said his death gave Iranians their "greatest chance" to reclaim their country. Democrats in Congress objected that he had acted without authorization. The White House said Republican and Democratic leaders had been briefed in advance.

The strikes had killed not only Khamenei but also the commander of the Revolutionary Guard Corps, the defense minister, and a senior security adviser—Ali Shamkhani, a figure who had shaped Iranian security policy for years. The leadership of the country was decapitated. The retaliation was massive. And the cycle was not finished. Trump had said he wanted to "annihilate" the Iranian navy and destroy the regional proxies Tehran supported. He offered the Revolutionary Guard immunity if they laid down arms, or "certain death" if they did not. The question now was whether Iran would strike again, whether the United States would follow through on its threat, and whether the region could absorb another round of escalation without tipping into a wider war that no one could control.

You have crossed our red line and must pay the price. We will deliver such devastating blows that you yourselves will be driven to beg.
— Mohammad Bagher Qalibaf, Iran's parliamentary speaker, in televised address Sunday
Iran just stated that they are going to hit very hard today, harder than they have ever hit before. THEY BETTER NOT DO THAT, HOWEVER, BECAUSE IF THEY DO, WE WILL HIT THEM WITH A FORCE THAT HAS NEVER BEEN SEEN BEFORE!
— President Donald Trump, in social media post
A Conversa do Hearth Outra perspectiva sobre a história
Inventor

Why did the U.S. and Israel choose this moment to strike? What changed?

Model

The intelligence showed Iran rebuilding its nuclear infrastructure after the previous year's strikes. The administration believed the window to act was closing. But there's also the political dimension—Trump wanted to project strength, to show he could move decisively. The timing during Ramadan, during the workweek, suggests they wanted maximum impact.

Inventor

What happens to Iran now without Khamenei? Is the government collapsing?

Model

Not immediately. They formed a council to govern until a new supreme leader is chosen. But the real question is whether the clerical establishment can hold together. Khamenei had final say on everything. Now there's no obvious successor, no one with his authority. You're seeing both celebration and mourning in the streets—that fracture is real.

Inventor

The school that was hit—was that intentional?

Model

The U.S. military says it's looking into reports. But a girls' school in southern Iran, 115 people dead—that's not a military target by any definition. Whether it was a targeting error or collateral damage from strikes on nearby facilities, the effect is the same. It hardens Iranian public opinion against the U.S., even among people who might have welcomed Khamenei's death.

Inventor

What about the oil markets? Is that the real danger here?

Model

A third of the world's seaborne oil passes through the Strait of Hormuz. If Iran decides to make that strait unsafe for commercial traffic, global energy prices spike immediately. That's not a distant threat—it's the leverage Iran has. The strikes on the Gulf states, the drones hitting airports and bases, that's Iran signaling it can reach anywhere in the region.

Inventor

Trump said he wanted to annihilate the Iranian navy. Is he serious?

Model

He's serious about the threat. Whether he follows through depends on what Iran does next. He's painted himself into a corner—he said if they strike again, he'll hit them with force "never seen before." If they do strike again and he doesn't respond at that level, he looks weak. If he does respond, you're in a full regional war.

Inventor

Could this have been avoided?

Model

That depends on whether you believe Iran's nuclear program was an existential threat or whether you think the previous strikes had already degraded it enough. Trump clearly believed it was still dangerous. Iran clearly believed it had the right to enrich uranium. Those positions were incompatible. Once you have that kind of fundamental disagreement, and you have the military capability to act, avoidance becomes very difficult.

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