For the many cancer survivors left to endure years of bladder bleeding after pelvic radiation, medicine has long offered little more than management and resignation. A small but carefully conducted phase II trial now suggests that chlorophyllin — a derivative of the pigment that makes plants green — may interrupt that suffering in meaningful ways, achieving meaningful remission in nearly three-quarters of patients. The finding does not yet close the question, but it opens a door that has been shut for decades, reminding us that relief sometimes arrives from unexpected and ancient sources.
Chlorophyllin shows promise for radiation-induced bladder bleeding in phase II trial
Chronic hemorrhagic cystitis affects 5-15% of pelvic radiotherapy patients, causing persistent urinary bleeding and reduced quality of life for cancer survivors.